Malaria Host Pathogen Interaction Center (MaHPIC) Experiment 23 (E23) Clinical Results

Experiment 23: M. mulatta infected with P. cynomolgi B strain to produce and integrate clinical, hematological, parasitological, and omics measures of acute primary infection and relapses. This clinical results dataset contains measures of disease infection including counts and calucations for: CBCs, reticulocytes, parasitemias, and downstream immunological, functional genomic, lipidomic, proteomic, and metabolomic measurements. Results also include data and metadata from veterinarians on all facets of animal access, including, but not limited to: treatments, hematology, biochemical analyses, parasitology, bacteriology, and surgery statistics, etc. Data were collected from animal arrival at research facility to the end of the experiment, including post-experiement curative treatments. Results also include documentation of data collection and analysis methods and supporting clinical matarials that differentiate between 'Idealized' and 'Actual' disease progression. This is an iteration of MaHPIC Experiment 04 with the same parasite-host combination and sampling and treatment adjustments made, and this is the first in a series of experiments that includes subsequent homologous (Experiment 24, P. cynomolgi B strain) and heterologous (Experiment 25, P. cynomolgi strain ceylonensis) challenges of individuals from the Experiment 23 cohort. Please see the file 'E23M99MEMmCyDaWB_README-PlasmoDB-09242018-V1_MULTIPL.txt' for a full description of this dataset and for instructions on how to access other datasets from this experiment. Please see https://plasmodb.org/plasmo/mahpic.jsp for descriptions and locations of all public MaHPIC datasets.