Unraveling the Evolutionary Origin of Complex Topologies

Maps when topological entanglement (knots, slipknots, lasso motifs) emerged across protein families using sequence, structure, and phylogenetic data. Tests functional consequences and sequence associations with protein topology across species.

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Author Ellinor Haglund
Last Updated September 10, 2026, 18:10 (UTC)
Published August 5, 2026, 18:10 (UTC)
Citation Ellinor Haglund 2026. Unraveling the Evolutionary Origin of Complex Topologies. CyVerse Data Commons.
Description Maps when topological entanglement (knots, slipknots, lasso motifs) emerged across protein families using sequence, structure, and phylogenetic data. Tests functional consequences and sequence associations with protein topology across species.
PublicationYear 2026
Publisher CyVerse Data Commons
Rights This material is based upon work supported by the U.S. National Science Foundation under Award No. #2335029. Any opinions, findings and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the U.S. National Science Foundation.
Subject protein topology, knots, slipknots, evolutionary origin, structure-function relationships, phylogenetics
de_created_date 2026-03-04T17:26:48Z
de_modified_date 2026-07-28T22:07:47Z